# CRISPR Brief — Warm Intro Template
## Draft: personalize before use. Do not send without swapping the trigger line.

---

### LinkedIn Connection Request Note

```
Hi [Name] — I came across your work on [specific deal / company / publication] 
and have been tracking the CRISPR gene-editing deal space for a while.

I've been putting together a twice-monthly brief that synthesizes the one bioRxiv 
preprint, one FDA filing, and one pipeline move that actually matter for VC scouts 
and associates each cycle. Written for deal screening, not broad biotech coverage.

Issue Zero is free: https://store-v2-khaki.vercel.app/crispr-brief-issue-zero.html
No credit card, no account needed.

Happy to share if it's useful for your deal flow.
```

> **LinkedIn note character count: ~250 chars** (under LinkedIn's 300-char connection limit)  
> **The trigger line must be personalized.** Replace `[specific deal / company / publication]` with something specific to the contact's recent work — a deal they worked on, a company they mentioned, a talk they gave. Generic versions ("I see you're in biotech") are not warm.

---

### Email Version

**Subject line:** CRISPR Brief — for biotech scouts and VC associates tracking deal flow

```
Hi [Name],

I came across your work on [specific trigger — deal, company, or publication] 
and have been following the CRISPR gene-editing deal space for a while.

I've been putting together a twice-monthly brief — CRISPR Brief — that synthesizes 
the one bioRxiv preprint, one FDA filing, and one pipeline move that actually 
matter for VC scouts and associates each cycle. It's written specifically for 
deal screening rather than broad biotech coverage.

Issue Zero is free — no credit card, no account needed:
https://store-v2-khaki.vercel.app/crispr-brief-issue-zero.html

Happy to share if it would be useful for your deal flow.

[Your name]
```

> **Email timing:** Send Tuesday–Thursday, before 10am recipient local time. Do not send Friday afternoon or weekends.  
> **Trigger is required.** Without a specific, accurate trigger, this is cold email. The warm intro only works when the trigger is genuine and specific to the recipient's actual recent work.

---

### Personalization checklist (do this before every send)

- [ ] Trigger line replaced with something specific to the recipient's actual recent work
- [ ] One-pager URL confirmed live (run: `curl -s -o /dev/null -w "%{http_code}" https://store-v2-khaki.vercel.app/crispr-brief-issue-zero.html`)
- [ ] [Your name] replaced with owner's actual first name
- [ ] If contact is at a specific firm, check the firm's recent CRISPR-adjacent deals before sending

---

### What NOT to say in the warm intro

| Don't say | Why |
|---|---|
| "I thought of you" | Vague, no trigger, feels like spam |
| "You might be interested in this newsletter" | Weak value prop, no specificity |
| "Can I send you my newsletter?" | Asking permission delays action; just send the link |
| Any price or subscription mention | Price comes after Issue Zero; not in the intro |
| "It's only $10/mo" | Do not mention price in warm outreach; the one-pager handles pricing |

---

### The funnel this template fits into

```
Owner sends warm intro (this template, personalized)
  → Contact clicks one-pager URL
  → Reads Issue Zero free (no gate)
  → Decides to subscribe (PayPal or Beehiiv, $10/mo early-bird)
  → CRISPR-specific thank-you page confirms subscription
  → First-dollar conversion
```

**The template's only job:** deliver the one-pager URL with enough context that the contact opens it rather than deleting unread. Everything else — the pitch, the price, the subscription — happens on the one-pager and downstream pages.